NCT02605226

Cryoablation Therapy or Radiotherapy Therapy for Stage III Prostate Cancer

A Prospective Multi-center Study to Compare the QOL and Efficacy of External Beam Radiation Therapy or Cryoablation Therapy for Stage III Prostate Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Tianjin Medical University Cancer Institute and Hospital · Academic / Other
• Sex: Male
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This trial is going to evaluate tumor control and quality of life in patients with prostate cancer treated with radiotherapy or cryoablation.

Detailed description

OBJECTIVES: * To determine the tumor control in patients with prostate cancer treated with radiotherapy or cryoablation * To determine the quality of life of these patients. OUTLINE: This is a multicenter study. Patients are stratified according to Gleason score (≥ 8 vs 7 vs ≤ 6), persistent prostatic specific antigen (PSA) at allocation (\> 0.5 ng/mL vs ≤ 0.5 ng/mL), participating center. Patient are allocated to two treatment arms.

Conditions

• Stage III Prostate Cancer

Interventions

Type	Name	Description
PROCEDURE	Cryoablation therapy	Cryoablation therapy
RADIATION	External beam radiation therapy	External beam radiation therapy
DRUG	bicalutamide	bicalutamide
DRUG	luteinizing-hormone releasing-hormone (LHRH) agonist	luteinizing-hormone releasing-hormone (LHRH) agonist

Timeline

• Start date: 2015-11-01
• Primary completion: 2017-12-01
• Completion: 2018-12-01
• First posted: 2015-11-16
• Last updated: 2017-06-12

Locations

1 site across 1 country: China