NCT02603315

Vascularity Impact on the Treatment Outcome in Malignant Pleural Mesothelioma(VITMPM)

To Assess the Correlation Between the Predictive Factor of Vascularity (CD74) in Malignant Pleural Mesothelioma and Treatment Results (Response Rate, and Overall Survival )

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 39 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to To assess the correlation between the predictive factor of vascularity (CD74) in malignant pleural mesothelioma and treatment results (response rate, and overall survival) .

Detailed description

This is a randomized controlled retrospective study through Examination of paraffin blocks of the patient selected to be included in the study for assessment of the selected vascularity marker of malignant pleural mesothelioma of both types . The CD74 (LN2) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed paraffin-embedded tissue sections using Immunohistochemistry test methods.

Conditions

• Malignant Pleural Mesotheliomas

Interventions

Type	Name	Description
OTHER	marker CD74 and vascular endothelial growth factor VEGF	correlate the result of vascularity test done on paraffin blocks on both types of malignant pleural mesothelioma patients diagnosed and receive treatment and evaluated after treatment

Timeline

• Start date: 2015-10-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2015-11-11
• Last updated: 2016-06-01

Locations

1 site across 1 country: Egypt