NCT02600195

Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality

Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality: A Cluster Randomised Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15,600 (estimated)
• Sponsor: Children's Hospital of Fudan University · Academic / Other
• Sex: All
• Age: 120 Days
• Healthy volunteers: Not accepted

Summary

This 4-year cluster randomized controlled trial aims to determine whether implementation of Evidence-based Practice for Improving Quality (EPIQ) method can reduce hospital-acquired infection in Chinese Neonatal Intensive Care Units (NICUs).

Detailed description

Following randomization into two groups, the intervention NICUs (n = 12) will receive training in the EPIQ method and then develop, implement, and document evidence-based practice changes to reduce hospital-acquired infection. Compliance with practice changes and neonatal outcomes will be monitored. NICUs will receive quarterly feedback on their progress, as well as access to implementation support. Control NICUs (n = 12) will collect neonatal data and continue to provide standard care. Study subjects will be all preterm infants born at \<34 weeks' gestation and admitted to participating NICUs during the trial (estimated n = 5,200 per year). Data analysis will be conducted to compare neonatal outcomes and health-care resources used between the intervention and control groups.

Conditions

• Nosocomial Infections

Interventions

Type	Name	Description
BEHAVIORAL	Evidence-based Practice for Improving Quality (EPIQ) method	The intervention NICUs (n = 12) will receive training in the Evidence-based Practice for Improving Quality (EPIQ) method and then develop, implement, and document evidence-based practice changes to reduce hospital-acquired infection. Compliance with practice changes and neonatal outcomes will be monitored. NICUs will receive quarterly feedback on their progress, as well as access to implementation support.

Timeline

• Start date: 2015-05-01
• Primary completion: 2018-04-01
• Completion: 2018-04-30
• First posted: 2015-11-09
• Last updated: 2018-08-07

Locations

24 sites across 1 country: China