NCT02600156

Focal Laser Ablation of Low to Intermediate Prostate Cancer Tumors

A Pilot Study to Evaluate Magnetic Resonance Thermal Image-Guided Focal Laser Ablation of Prostate Cancer Tumors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: Male
• Age: 45 Years
• Healthy volunteers: Not accepted

Summary

The primary purpose of this study is to evaluate the feasibility and safety of MRI-guided focal laser ablation (Laser-Induced Interstitial Thermal Therapy, LITT) to treat low-risk native prostate cancer.

Detailed description

The study is being done to evaluate the safety and effectiveness of Magnetic Resonance Imaging (MRI)-guided focal laser therapy with the Visualase Thermal Therapy System to treat low-risk prostate cancer tumors. Unlike surgery or radiotherapy which affects a large portion of the prostate or the entire organ, localized or focal therapy is intended to treat a small portion of tissue in which the cancer has been found by biopsy.

Conditions

• Prostate Cancer
• Prostate Adenocarcinoma
• Stage I Prostate Cancer AJCC v8
• Stage II Prostate Cancer AJCC v8
• Localized Prostate Carcinoma

Interventions

Type	Name	Description
PROCEDURE	Focal laser ablation of the prostate	MR guided laser ablation of the focal prostatic lesion which has been identified by MRI and biopsy prior to ablation.

Timeline

• Start date: 2015-09-01
• Primary completion: 2025-08-20
• Completion: 2025-12-09
• First posted: 2015-11-09
• Last updated: 2025-12-17

Locations

1 site across 1 country: United States