NCT02597907

Postoperative Nausea and Vomiting: Ramosetron Plus Aprepitant vs Palonosetron Plus Aprepitant

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 88 (actual)
• Sponsor: Kyungpook National University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to compare the antiemetic efficacy of aprepitant plus palonosetron versus aprepitant plus ramosetron in high risk patients undergoing laparoscopic cholecystectomy.

Detailed description

The purpose of this study was to compare the antiemetic efficacy of aprepitant plus palonosetron versus aprepitant plus ramosetron in high risk patients undergoing laparoscopic cholecystectomy. Study is performed during 24 hours after surgery.

Conditions

• Postoperative Nausea and Vomiting

Interventions

Type	Name	Description
DRUG	aprepitant	aprepitant 80 mg is given to all patients before surgery
DRUG	palonosetron	palonosetron 0.075 mg is given to patients in the aprepitant plus palonosetron group after induction of general anesthesia
DRUG	Ramosetron	ramosetron 0.3 mg is given to patients in the aprepitant plus ramosetron group after induction of general anesthesia

Timeline

• Start date: 2014-07-01
• Primary completion: 2015-05-01
• Completion: 2015-07-01
• First posted: 2015-11-05
• Last updated: 2017-04-25
• Results posted: 2017-04-25