NCT02597855

Short-term Efficacy of Intravitreal Afilibercept Depending on Subtypes of Polypoidal Choroidal Vasculopathy: Polypoidal Choroidal Neovascularization or Idiopathic Choroidal Vasculopathy

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 29 (actual)
• Sponsor: Yeungnam University College of Medicine · Academic / Other
• Sex: All
• Age: 45 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

To compare the short-term effect of intravitreal aflibercept injection between two subtypes of polypoidal choroidal vasculopathy

Detailed description

The subjects were classified into two subtypes (type 1 and type 2 polypoidal choroidal vasculopathy) based on the presence or the absence of both of a feeder and a draining vessels on indocyanine green angiography. All received intravitreal injection of aflibercept (2.0 mg) at baseline and months 1, 2 and 4.

Conditions

• Polypoidal Choroidal Vasculopathy

Interventions

Type	Name	Description
DRUG	Aflibercept	Total 4 times of intravitreal aflibercept injection was performed
DRUG	Indocyanine green angiography (intraveonus indocyanine green dye)	At initial visit, indocyanine green angiography was performed. After 1 month of third Aflibercept injection, indocyanine green angiography was performed to evaluate polyp closure.

Timeline

• Start date: 2015-09-01
• Primary completion: 2015-12-01
• Completion: 2016-08-01
• First posted: 2015-11-05
• Last updated: 2016-08-18
• Results posted: 2016-06-17

Locations

1 site across 1 country: South Korea