Trials / Completed
CompletedNCT02597595
Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Tanta University · Academic / Other
- Sex
- All
- Age
- 4 Years – 18 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to evaluate the cardioprotective effect of spirulina in children with beta thalassemia.
Detailed description
The aim of this study is to evaluate the cardioprotective effect of spirulina in children with beta thalassemia. this study will be carried on thirty children with beta thalassemia major from those attending the Hematology Unit of Pediatric department at Tanta University Hospital, and another thirty healthy children of matched age and sex will be enrolled as controls. all studied children will be subjected to careful history taking and through clinical examination. laboratory investigations will be done including complete blood count, hemoglobin electrophoresis, serum ferritin, liver and kidney functions, and troponin-1 plasma level. echocardiographic assessment of the cardiac functions will be done for all patients. Source data will be the patients medical records. oral spirulina will be given for studied patients for 3 months, and clinical examination, laboratory investigations and cardiac functions will be assessed at the time of inclusion in the study, and again after 3 months of regular spirulina supplementation. An informed consent will be obtained from parents of all included subjects. the results of this study will be tabulated and statistically analyzed using Statistical Package for the Social Sciences (SPSS).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | spirulina | oral spirulina (tablet=500mg) will be given to patients for 3 months in a dose of 250 mg/kg/day (maximum 4 gm) |
Timeline
- Start date
- 2014-11-01
- Primary completion
- 2017-10-01
- Completion
- 2017-10-01
- First posted
- 2015-11-05
- Last updated
- 2018-09-11
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT02597595. Inclusion in this directory is not an endorsement.