Clinical Trials Directory

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UnknownNCT02596243

Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E)

A Randomized, Double-blind, Placebo-controlled, Multi-center, Phase 2 Clinical Trial to Evaluate the Efficacy and the Safety of GX-188E, a DNA-based Therapeutic Vaccine, Administered Intramuscularly by Electroporation(EP) in HPV Type 16 and/or 18 Positive Patients With Biopsy-proven Cervical Intraepithelial Neoplasia Grade 2(CIN2), Grade 2/3 (CIN2/3), Grade 3(CIN3)

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
134 (actual)
Sponsor
Genexine, Inc. · Industry
Sex
Female
Age
18 Years – 60 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to access the efficacy and safety of GX-188E according the protocol in patients with Cervical Intraepithelial Neoplasia 2, 2/3 or 3 (CIN3)

Detailed description

Not provided

Conditions

Interventions

TypeNameDescription
BIOLOGICALGX-188E1mg of GX-188E administered IM using EP device at day 0, week 4 and week 12.
BIOLOGICALPlacebo0.5mL of Placebo administered IM using EP device at day 0, week 4 and week 12.

Timeline

Start date
2015-08-01
Primary completion
2018-03-01
Completion
2018-08-01
First posted
2015-11-04
Last updated
2017-07-12

Locations

16 sites across 3 countries: Estonia, South Korea, Ukraine

Source: ClinicalTrials.gov record NCT02596243. Inclusion in this directory is not an endorsement.