Trials / Completed
CompletedNCT02595476
Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus
The Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus Under Steady-state Remifentanil Analgesia
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Hôpital Armand Trousseau · Academic / Other
- Sex
- All
- Age
- 10 Years – 20 Years
- Healthy volunteers
- Not accepted
Summary
A standardized tetanic stimulation is applied to patients under propofol-remifentanil TCI, in a cross-over fashion, at two different levels of anesthesia monitored by the BIS: BIS 25 and BIS 55. Remifentanil target remains constant during the whole study period (1 ng/ml). Pupillary reflex dilation is recorded after each stimulation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Remifentanil | |
| DRUG | propofol | |
| DEVICE | TCI | |
| PROCEDURE | Tetanic stimulation | |
| DEVICE | Algiscan | Pupillometry |
Timeline
- Start date
- 2015-01-01
- Primary completion
- 2016-01-01
- Completion
- 2016-03-01
- First posted
- 2015-11-03
- Last updated
- 2017-04-04
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02595476. Inclusion in this directory is not an endorsement.