NCT02592486

The Immunogenicity of Simultaneous Administration of Quadrivalent Influenza Vaccine and 23-valent Pneumococcal Vaccine

A Randomized, Open-label, Parallel Design Study to Compare the Immunogenicity of Simultaneous Administration Versus Sequential Administration of Quadrivalent Influenza Vaccine and 23-valent Pneumococcal Vaccine

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 162 (actual)
• Sponsor: Kameda Medical Center · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The immunogenicity of simultaneous administration of quadrivalent influenza vaccine and pneumococcal vaccine was unknown. The purpose of present study is to compare the immunogenicity of simultaneous administration of influenza vaccine and pneumococcal vaccine with that of separate administration.

Detailed description

The immunogenicity of simultaneous administration of quadrivalent influenza vaccine and pneumococcal vaccine was unknown. We compare the immunogenicity of simultaneous administration of quadrivalent influenza vaccine and pneumococcal vaccine with that of separate administration. 162 Participants are randomly assigned to one of the two study groups; Simultaneous administration group: receive injections of pneumococcal vaccine and influenza vaccine simultaneously. Sequential administration group: receive injections of pneumococcal vaccine 2 weeks after the injection of the influenza vaccine. We compare the immunogenicity of the two groups.

Conditions

• Pneumococcal Pneumonia
• Influenza

Interventions

Type	Name	Description
BIOLOGICAL	Simultaneous administration of Pneumovax NP® and Fluvic HA syringe®	Injections of pneumococcal vaccine and influenza vaccine simultaneously.
BIOLOGICAL	Sequential administration of Pneumovax NP® and Fluvic HA syringe®	Injections of pneumococcal vaccine 2 weeks after the injection of the influenza vaccine.

Timeline

• Start date: 2015-11-01
• Primary completion: 2016-03-01
• Completion: 2016-08-01
• First posted: 2015-10-30
• Last updated: 2019-01-31
• Results posted: 2019-01-31

Locations

1 site across 1 country: Japan