Trials / Completed
CompletedNCT02590354
Analytical Treatment Interruption in HIV Positive Patients
Analytical Treatment Interruption in HIV Positive Patients With Low Viral Reservoir to Evaluate the Potential of a Functional Cure
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 114 (actual)
- Sponsor
- Institute of Tropical Medicine, Belgium · Academic / Other
- Sex
- All
- Age
- 18 Years – 64 Years
- Healthy volunteers
- Not accepted
Summary
HIV-1 infected patients with normal peripheral blood CD4+ T-cell counts and undetectable viral load will be recruited in four Belgian HIV reference centers. Selected patients will undergo a two-step screening in which a viral reservoir measurement will be performed and among those with a very low viral reservoir an analytical treatment interruption of their longstanding antiretroviral therapy (ART). There is no randomization foreseen. Patients will receive an intense clinical and laboratory follow-up during 48 weeks followed by 12 weeks post intervention.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | ART interruption |
Timeline
- Start date
- 2016-01-25
- Primary completion
- 2018-06-22
- Completion
- 2018-06-22
- First posted
- 2015-10-29
- Last updated
- 2019-09-24
- Results posted
- 2019-09-24
Locations
4 sites across 1 country: Belgium
Source: ClinicalTrials.gov record NCT02590354. Inclusion in this directory is not an endorsement.