Trials / Completed
CompletedNCT02589613
Glucose and Fructose Stimulated Brain Activity in Obese Subjects
Effects of Acute Glucose and Fructose Ingestion on Brain Activity in Obese Volunteers
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- University Hospital, Basel, Switzerland · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The objective is to investigate neuro-anatomical correlates of the regulation of energy intake by means of functional MRI. Administration of glucose as well as fructose is followed by functional brain MRI, and findings are correlated with serum glucagon-like peptide 1 (GLP-1) levels as an endogenous satiety signal in obese humans.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | tap water | 300ml tap water via nasogastric tube |
| DIETARY_SUPPLEMENT | Glucose | 300ml tap water with 75g Glucose via nasogastric tube |
| DIETARY_SUPPLEMENT | Fructose | 300ml tap water with 25g Fructose via nasogastric tube |
Timeline
- Start date
- 2013-10-01
- Primary completion
- 2014-06-01
- Completion
- 2014-06-01
- First posted
- 2015-10-28
- Last updated
- 2015-10-28
Source: ClinicalTrials.gov record NCT02589613. Inclusion in this directory is not an endorsement.