NCT02587546

Thulium Contact Laser of Laryngotracheal Stenosis

Thulium Contact Laser in the Treatment of Tumorous and Non-tumorous Laryngotracheal Stenosis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: University Hospital Ostrava · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to compare results of the treatment of tumorous and non-tumorous laryngotracheal stenosis using thulium contact laser versus carbon dioxide laser used in the past.

Detailed description

Laryngotracheal stenosis is a serious disease significantly worsening the quality of life. Impaired breathing often leads to tracheotomy, deterioration of the voice leads to communication problems with others and swallowing problems are often present, as well The main causes of laryngotracheal stenosis are post intubation and post tracheostomy conditions, inflammatory process (often autoimmune), tumors (mainly squamous cell carcinoma and chondroma) and trauma. Within the last years there is substantial shift in the treatment strategy from open surgery to endoscopic techniques. However, surgical treatment is often difficult due to demanding exposure of tumor and problematic margins control. In recent years there has been a development of particular techniques of endoscopic resection of tumors and non-malignant laryngeal glottic and subglottic stenosis using a carbon dioxide (CO2) laser with promising improvement of treatment results. However, CO2 laser has some limitations, particularly in the treatment of tumors spreading into anterior commissure, because CO2 laser beam cannot get "around the corner". Moreover, subglottic area is also difficult to be reached by CO2 laser beam. Therefore, contact laser with adjustable manipulators with possibility to bend tip of manipulator according to the actual need seems to be of some advantage.

Conditions

• Laryngeal Carcinoma
• Bilateral Vocal Cord Paresis
• Subglottic Stenosis

Interventions

Type	Name	Description
PROCEDURE	laryngeal carcinoma	treatment of laryngeal carcinoma using thulium contact laser
PROCEDURE	bilateral vocal cord paralysis	treatment of bilateral vocal cord paralysis using thulium contact laser
PROCEDURE	subglottic stenosis	treatment of subglottic stenosis using thulium contact laser

Timeline

• Start date: 2015-10-01
• Primary completion: 2018-07-01
• Completion: 2018-09-01
• First posted: 2015-10-27
• Last updated: 2019-08-01

Locations

1 site across 1 country: Czechia