NCT02587416

Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

A Study of the Effect of Oral, Multiple-Dose 300 mg and 900 mg Gemcabene (CI-1027) Administration on the Steady-State Pharmacokinetics of Atorvastatin 80 mg

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: NeuroBo Pharmaceuticals Inc. · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the effect of gemcabene on the pharmacokinetics of atorvastatin 80 mg

Conditions

• Hypercholesteremia

Interventions

Type	Name	Description
DRUG	Gemcabene 300 mg	1x300 mg gemcabene tablets orally once daily (QD) for 11 days
DRUG	Gemcabene 900 mg	3x300 mg Gemcabene tablets orally once daily (QD) for 11 days
DRUG	Atorvastatin	2x40 mg Atorvastatin tablets orally once daily (QD)

Timeline

• Start date: 2002-11-01
• Primary completion: 2002-12-01
• Completion: 2002-12-01
• First posted: 2015-10-27
• Last updated: 2020-04-09