Clinical Trials Directory

Trials / Completed

CompletedNCT02587000

Adenomyosis and Ulipristal Acetate

Pilot Phase II, Randomized , and Control in Double Blind Placebo Effectiveness a 3 Months on Bleeding Fibroids Treatment With ULIPRISTAL ACETATE 10 mg/Day in Patients Suffering From Symptomatic Endometriosis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
26 (actual)
Sponsor
Assistance Publique - Hôpitaux de Paris · Academic / Other
Sex
Female
Age
30 Years – 50 Years
Healthy volunteers
Not accepted

Summary

Evaluation of efficiency of selective progesterone receptor modulators (SPRM) (Ulipristal acetate) on bleeding control and pain for patients with adenomyosis and wish to keep fertility.

Detailed description

After inclusion according to criteria, 2 arms : placebo and Ulipristal acetate (UA) 10mg with randomisation, 1 patient with placebo for 3 patients with UA. 48 patients will be included in this trial. The end point will be the bleeding evaluated by Pictorial Blood-loss Assessment Chart (PBAC) score, the amenorrhea rate and the pain evaluated with visual analogic scale.

Conditions

Interventions

TypeNameDescription
DRUGUlipristal acetate
DRUGPlacebo

Timeline

Start date
2015-06-16
Primary completion
2018-02-02
Completion
2020-03-17
First posted
2015-10-27
Last updated
2022-09-27

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT02587000. Inclusion in this directory is not an endorsement.