Trials / Terminated
TerminatedNCT02585752
A Study of Expiratory Pressure Modulation in Moderate to Severe COPD Patients - Phase 1b
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- ResMed · Industry
- Sex
- All
- Age
- 18 Years – 100 Years
- Healthy volunteers
- Not accepted
Summary
Dynamic pulmonary hyperinflation (DH) and intrinsic positive end-expiratory pressure (PEEP) are well known problems in COPD patients with acute and chronic respiratory failure. Measurement of intrinsic PEEP level during both, invasive and non-invasive ventilation is of major importance since in some circumstances (e.g. during exercise or during exacerbations) it can significantly increase respiratory workload of COPD patients. Extrinsic PEEP applied during both, invasive and noninvasive ventilation is used to overcome intrinsic PEEP and therefore to avoid or reduce dynamic hyperinflation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Noninvasive ventilation | Expiratory pressure modulation |
Timeline
- Start date
- 2015-10-01
- Primary completion
- 2017-09-30
- Completion
- 2017-11-24
- First posted
- 2015-10-23
- Last updated
- 2018-04-23
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02585752. Inclusion in this directory is not an endorsement.