NCT02585297

The Presence of Microbes in the Sperm and Their Impact on Sperm Capacitation and IVF Treatment

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Meir Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Study Goals: 1. Finding the prevalence of bacteria of the sperm in an innovative and more accurate methode 2. Understanding the effect of microbes on the process of capacitation 3. The impact of microbes in the sperm on IVF success rate 4. Finding the incidence of vaginal bacteria and their relationship to bacteria of the sperm 5. The impact of vaginal flora on IVF success rate

Detailed description

Prospective non interventional study in the Department of Life Sciences, Bar-Ilan University and IVF Unit at Meir Hospital. The control group consisting of 50 semen samples from men with no sperm problems and 50 vaginal samples from their partners. The study group consisting of 50 semen samples from men with male fertility problems and 50 vaginal samples from their partners. The semen taken from the remains after fertilization of the IVF laboratory. (Liquid otherwise routinely thrown). Vaginal samples taken from women undergoing IVF treatment under anesthesia after informed consent. Enrollment also collect the following data: age, race, chronic illnesses, past surgeries and former fertility treatments. Data will be collected through anamnesis of the patient or the medical file after consent.

Conditions

• Infertility

Interventions

Type	Name	Description
OTHER	no intervention

Timeline

• Start date: 2015-10-01
• Primary completion: 2017-10-01
• First posted: 2015-10-23
• Last updated: 2015-10-23