Trials / Unknown
UnknownNCT02584582
The Effect of GLP-1 on Postprandial Glucagon Secretion Independent of The Gastric Emptying Rate
The Effect of GLP-1 on Postprandial Glucagon Secretion During Prolonged and Intermittent Stimulation of the GLP-1 Receptor Independent of The Gastric Emptying Rate. A Randomized, Open-label Study in People With Type 1 Diabetes
- Status
- Unknown
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- Sponsor
- Hvidovre University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Aim: To investigate the glucagonostatic effect of glucagon-like peptide-1 (GLP-1) independent of the gastric emptying rate.
Detailed description
Aim: To investigate the glucagonostatic effects of glucagon-like peptide-1 (GLP-1) during prolonged and intermittent stimulation of the GLP-1 receptor independent of the gastric emptying rate. Glucagon concentrations will be measured following a liquid meal administered in duodenum at baseline and after exenatide, and liraglutide treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Liraglutide | |
| DRUG | Exenatide | |
| PROCEDURE | Liquid meal test | |
| OTHER | No drug (Baseline day) |
Timeline
- Start date
- 2015-07-01
- Primary completion
- 2015-11-01
- First posted
- 2015-10-22
- Last updated
- 2015-10-22
Source: ClinicalTrials.gov record NCT02584582. Inclusion in this directory is not an endorsement.