NCT02579551

Effectiveness of Narrow Margins in Patients With Low-Risk Basal Cell Carcinoma Undergoing Surgery

Long Term Prospective Study Evaluating Effectiveness of Narrow Margins for Low-Risk Facial Basal Cell Carcinomas

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 179 (actual)
• Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This clinical trial studies the effectiveness of narrow margins in patients with low-risk basal cell carcinoma undergoing surgery to remove skin lesions on the face. A margin is the area of normal tissue around a tumor taken out during surgery to make sure all of the cancer is removed. This clinical trial studies tissue samples to determine the least amount of tissue that must be removed to give an acceptable cure rate. This may allow less normal tissue to be removed from patients and may be a less expensive surgery.

Detailed description

PRIMARY OBJECTIVES: I. To determine the success rate of narrow margin excisions of low-risk facial basal cell carcinoma (BCC). SECONDARY OBJECTIVES: I. To determine the narrowest excision margin for low-risk facial BCC that gives an acceptable (95%) cure rate over a 3 year follow-up period.

Conditions

• Skin Basal Cell Carcinoma

Interventions

Type	Name	Description
PROCEDURE	Therapeutic Conventional Surgery	Undergo surgical excision

Timeline

• Start date: 2011-12-07
• Primary completion: 2014-02-01
• Completion: 2017-05-04
• First posted: 2015-10-19
• Last updated: 2025-04-29

Locations

1 site across 1 country: United States