NCT02579148

Collagen Scaffolds Loaded With HUCMSCs for the Improvement of Erectile Function in Men With Diabetes

Collagen Scaffolds Loaded With Human Umbilical Cord Mesenchymal Stem Cells for the Improvement of Erectile Function in Men With Diabetes

• Status: Withdrawn
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Leilei Zhu · Academic / Other
• Sex: Male
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The intent of this clinical study is to answer the questions: 1) is the proposed treatment feasible; 2) is treatment effective in improving the disease pathology of patients with diagnosed diabetic erectile dysfunction.

Detailed description

Intracavernous transplantation of stem cells has been shown to improve erectile function in some preclinical studies. However, inadequate cell homing to damaged sites limited its functions. The investigators explore the effect of HUCMSC on improving erectile function of diabetic men, and whether collagen scaffolds contribute to long-term cell retention in the corpus cavernous and improves erectile function of diabetic men.

Conditions

• Erectile Dysfunction
• Type 1 Diabetes Mellitus
• Type 2 Diabetes Mellitus

Interventions

Type	Name	Description
BIOLOGICAL	HUCMSC injection	The subjects will receive intracavernous injection of HUCMSC.'
BIOLOGICAL	collagen scaffolds/HUCMSC injection	The subjects will receive intracavernous injection of the mixture of collagen scaffolds and HUCMSC respectively.'

Timeline

• Start date: 2015-09-01
• Primary completion: 2016-12-01
• Completion: 2017-04-01
• First posted: 2015-10-19
• Last updated: 2016-04-08

Locations

1 site across 1 country: China