Trials / Completed
CompletedNCT02577497
Effect of Extra- Fine Versus Coarse-Particle Inhaled Corticosteroids (ICS) on Ventilation Heterogeneity in Children With Poorly Controlled Asthma
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 31 (actual)
- Sponsor
- University of Virginia · Academic / Other
- Sex
- All
- Age
- 6 Years – 17 Years
- Healthy volunteers
- Not accepted
Summary
The primary objective of the study is to show that ventilation heterogeneity identified by hyperpolarized helium-3 lung MRI is prevalent children with poorly controlled asthma despite guidelines-based treatment with ICS. The secondary objective is to demonstrate whether or not eight weeks of treatment with extra-fine particle ICS (HFA-BDP) improves ventilation heterogeneity compared to treatment with a coarse particle ICS (fluticasone HFA or dry powder).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | beclomethasone | |
| DRUG | fluticasone |
Timeline
- Start date
- 2016-06-01
- Primary completion
- 2018-07-06
- Completion
- 2018-07-06
- First posted
- 2015-10-16
- Last updated
- 2018-10-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02577497. Inclusion in this directory is not an endorsement.