NCT02576392

FDA: Lowering Orthopedic Opioid Dosing (FLOOD)

Reducing the Use of Opioid Therapy Following Orthopedic Surgery: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 561 (actual)
• Sponsor: Kaiser Permanente · Academic / Other
• Sex: All
• Age: 20 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

This randomized trial evaluates an intervention to minimize use of opioids following total hip and total knee replacement. Half the participants will receive an intervention (mailed educational materials, followed by a pharmacist call), and half will receive usual care.

Detailed description

Surgeons and anesthesiologists prescribe opioids and other analgesic medications for acute, post-surgical pain. Recent studies have reported that some patients persist in taking opioids for months beyond the surgery. While opioids are commonly used for pain management following surgery, patients and their providers often don't have a planned method to optimize opioid exposure. This can lead to patients entering a cycle of opioid use that is difficult to manage, because, as opioid exposure is continued, pain relief is reduced and side effects increase. The investigators' study is aimed at reducing opioid exposure following total hip and total knee replacement.

Conditions

• Post-operative Pain

Interventions

Type	Name	Description
BEHAVIORAL	Intervention	Intervention consisted of a mailing 2 weeks prior to surgery, another 2 weeks post surgery, and a pharmacist intervention if a refill of opioid medication was requested within 90 days of surgery.

Timeline

• Start date: 2015-07-01
• Primary completion: 2017-03-31
• Completion: 2017-03-31
• First posted: 2015-10-15
• Last updated: 2017-06-06