NCT02574039

Oat Phenolics Bioavailability

Absorption, Metabolism and Excretion of Oat Phenolic Acids in Healthy Men.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: University of Reading · Academic / Other
• Sex: Male
• Age: 25 Years – 65 Years
• Healthy volunteers: Accepted

Summary

A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oat bran	66g oat bran made up in 350ml skimmed milk
DIETARY_SUPPLEMENT	refined grain	refined grain product and 350ml skimmed milk

Timeline

• Start date: 2015-07-01
• Primary completion: 2015-10-01
• Completion: 2015-10-01
• First posted: 2015-10-12
• Last updated: 2015-10-12

Locations

1 site across 1 country: United Kingdom