NCT02572362

Secondary Cancer Risk After Radiation Therapy for Rectal Cancer

Estimation of Second Cancer Risk in Patients Planned With Different Radiotherapy Regimes for Rectal Cancer - A Planning Study and Model-based Analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: Kantonsspital Graubuenden · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Retrospective study comparing dose distribution of 3D conformal radiotherapy (3DCRT) and volumetric-modulated arc therapy (VMAT) to estimate secondary cancer risk for patients having had radiation therapy for rectal cancer. Twenty-five patients are included in this study. Planning CT scans are used for comparison of dose distribution and calculation of second cancer risk.

Detailed description

A model-based Analysis calculating the organ-specific excess lifetime attributable risk using the planning CT data sets of 25 patients to estimate second cancer risk for patients after radiotherapy for rectal cancer comparing conventional 3DCRT with VAMT techniques.

Conditions

• Neoplasms, Second Primary

Interventions

Type	Name	Description
OTHER	No intervention in this retrospective study	No Intervention in this retrospective Analysis. All patients included did receive Radiation therapy Independent of this study

Timeline

• Start date: 2015-08-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2015-10-08
• Last updated: 2016-12-13

Locations

1 site across 1 country: Switzerland