NCT02570399

High Dose SBRT for Abdominal-Pelvic Lymph Nodal Lesions in Oligometastatic Patients

Feasibility Study of High Dose Stereotactic Body Radiation Therapy (SBRT) for Lymph Nodal Lesions in Oligometastatic Patients for Genito-urinary, Gastro-intestinal and Gynaecological Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: Istituto Clinico Humanitas · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This is a prospective, multicentric, phase II and feasibility study aimed to address early and late side effects of hypofractionated ablative radiotherapy for oligometastatic patients with lymph node metastases for genito-urinary, gastro-intestinal and gynaecological cancer.

Detailed description

The purpose of this prospective, multicentric, phase II study is to determine the feasibility of Stereotactic Body Radiation Therapy in stage IV selected oligometastatic patients, by looking at acute and late toxicity. Investigators also want to verify what is the impact of local control in irradiated metastatic foci in the context of the systemic disease, how local control can affect disease free survival and overall survival, and moreover quality of life of patients treated.

Conditions

• Lymph Node Cancer Metastatic

Interventions

Type	Name	Description
RADIATION	Oligometastatic patients with abdominal-pelvic lymph nodes	Hypofractionated ablative radiation therapy for oligometastatic patients with lymph node metastases

Timeline

• Start date: 2015-02-26
• Primary completion: 2019-03-26
• Completion: 2022-12-01
• First posted: 2015-10-07
• Last updated: 2021-10-06

Locations

1 site across 1 country: Italy