Trials / Completed
CompletedNCT02569684
Effects of Prebiotics on GLP-1 in Type 2 Diabetes
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 37 (actual)
- Sponsor
- Oslo University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to compare the effects of prebiotics versus placebo on blood concentrations of glucagon-like peptide-1 in subjects with diabetes type 2.
Detailed description
We looked at 6 weeks supplementation with a prebiotic fibre mix of inulin and FOS. Cross over design compared to maltodextrin as placebo. Additional outcome measures: blood glucose, insulin, GLP-2, ghrelin, PYY and leptin after a standardized mixed meal test. Also measured changes in microbiota composition and SCFA in feces before and after intervention/placebo periods, and subjective measures of appetite.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Prebiotic fibers: oligofructose and inulin | |
| DIETARY_SUPPLEMENT | Maltodextrin |
Timeline
- Start date
- 2015-10-01
- Primary completion
- 2018-01-01
- Completion
- 2019-12-01
- First posted
- 2015-10-07
- Last updated
- 2020-09-16
Locations
1 site across 1 country: Norway
Source: ClinicalTrials.gov record NCT02569684. Inclusion in this directory is not an endorsement.