NCT02568358

DNA-based Testing in BAL of Lung Transplant Recipients With Suspected Non-viral Lower Respiratory Tract Infection

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 48 (estimated)
• Sponsor: Hannover Medical School · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Lung transplantation (LTx) , DNA-based testing. Performance of DNA-based testing of bacterial and fungal pathogens in comparison to standard testing. Experimental intervention: DNA-based testing of BAL fluid.

Detailed description

Cohen's kappa of any pathogen isolation by DNA-based testing vs. standard cultures in comparison to the final diagnosis of non-viral lower respiratory tract infection.

Conditions

• Lower Respiratory Tract and Lung Infections

Interventions

Type	Name	Description
OTHER	Experimental Intervention: DNA-based testing of BAL fluid	DNA based testing needs 4.5 hours lab time in addition to standard testing

Timeline

• Start date: 2015-10-01
• Primary completion: 2016-04-01
• Completion: 2016-06-01
• First posted: 2015-10-05
• Last updated: 2015-10-05