NCT02567227

Cognitive Remediation to Improve Mobility in Sedentary Seniors

Cognitive Intervention to Improve Simple and Complex Walking

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 383 (actual)
• Sponsor: Albert Einstein College of Medicine · Academic / Other
• Sex: All
• Age: 70 Years
• Healthy volunteers: Accepted

Summary

The investigators propose to conduct a single-blind randomized clinical trial to test the efficacy of a computerized cognitive remediation intervention program on improving locomotion in sedentary seniors, a group at an especially high risk for disability. The hypothesis is that executive functions will respond to the cognitive remediation program and in turn enhance locomotion.

Detailed description

Emerging evidence indicates that Executive Functions play an important role in maintaining locomotion in aging and preventing mobility disabilities. However, use of cognitive training programs to improve executive functions as a strategy to increase mobility has not been explored. Exciting results from the preliminary study support the efficacy and feasibility of the cognitive remediation approach to improve locomotion in older adults. The premise of this clinical trial is that disability among seniors is a potentially preventable chronic condition rather than an irreversible consequence of aging and disease. The investigators proposed novel approach to locomotion has the potential to shift treatment paradigms in the field of disability by introducing cognitive approaches to mobility that can be applied to prevention and rehabilitation in diverse settings. Through this 'proof of concept' secondary prevention trial the investigators will fill an important gap in knowledge for practicing evidence-based medicine and developing effective interventions for a major health outcome affecting a substantial proportion of the U.S. aging population.

Conditions

• Mobility Limitation
• Motor Activity
• Difficulty Walking
• Cognitive Ability General

Interventions

Type	Name	Description
OTHER	Cognitive Remediation	This computerized program has successfully been used by seniors in different settings. It trains a number of cognitive processes including attention and Executive Function.The Cognitive Remediation (CREM) training is constructed based on the program's built in baseline cognitive evaluation.
OTHER	Active Control	Computer, multimedia and group based health education programs.

Timeline

• Start date: 2016-03-01
• Primary completion: 2020-06-01
• Completion: 2020-08-01
• First posted: 2015-10-02
• Last updated: 2024-02-28
• Results posted: 2021-06-07

Locations

1 site across 1 country: United States