NCT02563678

Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines

Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines: a Pilot Study

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Intermountain Health Care, Inc. · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

In this small pilot study, participants (patients and healthy volunteers) will have blood drawn before and after the study intervention (hyperbaric chamber session or normal pressure oxygen breathing. This blood will be analyzed for neutrophil oxidative burst and cytokine analysis.

Detailed description

The investigators are interested in studying the influence of hyperbaric oxygen on neutrophils (a kind of white blood cell) and cytokines (cell proteins). Hyperbaric oxygen can enhance the way the immune system works, but the investigators don't fully know how that happens. the investigators are doing this study to learn more about this question.

Conditions

• Infection

Interventions

Type	Name	Description
DRUG	Hyperbaric Oxygen	Hyperbaric oxygen therapy
OTHER	Hyperbaric Air/Oxygen	Breathing air inside a hyperbaric chamber, then breathing oxygen inside a hyperbaric chamber
OTHER	Normobaric oxygen	Breathing 100% oxygen at normal, atmospheric pressure

Timeline

• Start date: 2015-04-01
• Primary completion: 2023-12-01
• Completion: 2023-12-01
• First posted: 2015-09-30
• Last updated: 2022-08-04

Locations

2 sites across 1 country: United States