NCT02554500

Bone Microcirculation After Remote Ischemic Preconditioning

Effects of Remote Ischemic Preconditioning in Bone Microcirculation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: University Hospital Schleswig-Holstein · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

In trauma surgery and hand surgery treatment strategies of none healing bone fractures aim at replacing pseudarthrosis by well vascularized bone and improving microcirculation. Although previous studies indicate that remote ischemic preconditioning (RIPC) can accelerate bone healing in case of non-union, only a few studies focused on the elucidation of its mechanisms of action. Therefore, the aim of this study is to evaluate the microcirculatory effects of remote ischemic preconditioning (RIPC) on scaphoid bones and metacarpal bones and metatarsal bones in a human in-vivo setting for the first time.

Conditions

• Intact Scaphoid Bone
• Intact Metacarpal Bone
• Fractured Scaphoid Bone
• Fractured Metacarpal Bone

Interventions

Type	Name	Description
PROCEDURE	Remote Ischemic Preconditioning (by Blood Pressure Cuff)	Remote Ischemik Preconditioning is performed using a Blood Pressure Cuff with a pressure slightly above patients' blood pressure on the upper arm.

Timeline

• Start date: 2015-09-01
• Primary completion: 2023-02-01
• Completion: 2023-02-01
• First posted: 2015-09-18
• Last updated: 2023-02-24

Locations

1 site across 1 country: Germany