NCT02553720

The ATLANTIS Trial

Aquatic Therapy to Lower Adverse and Negative Effects of Venous Thrombosis and InSufficiency

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 181 (actual)
• Sponsor: Arizona Cardiovascular Consultants · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test whether addition of aquatic exercise to conventional treatment helps reduce the adverse outcomes of chronic venous insufficiency including CVI resulting from venous thrombosis.

Detailed description

Post-thrombotic syndrome (PTS) develops in approximately 25-60% of patients with acute lower extremity deep venous thrombosis (DVT) depending on severity, chronicity, anatomic level of involvement and efficacy of anticoagulation.The frequency increases with occlusive iliac venous thrombosis. PTS results in significant morbidity and a staggering toll on health careresources . PTS is reduced by early percutaneous endovenous intervention and administration of new oral anticoagulants. There are conflicting results on the efficacy of exercise . In general, exercise has been useful in activation of the muscle pump and improvement of symptoms. There are no data about exercise in a swimming pool. Both walking in water or swimming reduce the effect of joint contact and therefore pain which is particularly useful in patients with arthritis or heavyweight. Furthermore with less effect of gravity, absorption of dependent edema would be faster. Dry skin becomes hydrated and the chlorine of water can exert antiseptic properties. There are no data on the role of aquatic activity in the reduction of measures of venous insufficiency.The purpose of this study is to assess whether encouragement of patients to perform aquatic activity in addition to baseline treatment would positively impact chronic venous insufficiency.

Conditions

• Chronic Venous Hypertension Due to Deep Vein Thrombosis
• Venous Reflux

Interventions

Type	Name	Description
OTHER	exercise in water	The patients will be instructed to perform walking or swimming for 15 minutes, 3 times a week for 3 months in a swimming pool in addition to conventional management
OTHER	aquatic activity plus conventional management	walking in water or swimming for 15 minutes, 3 times a week for 3 months in a swimming pool in addition to conventional management

Timeline

• Start date: 2015-09-01
• Primary completion: 2016-07-01
• Completion: 2018-01-01
• First posted: 2015-09-18
• Last updated: 2020-07-23

Locations

1 site across 1 country: United States