NCT02552342

Corticosteroid Therapy for Severe Community-Acquired Pneumonia

Efficacy of Methylprednisolone in Severe Community-acquired Pneumonia，A Multi-center Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 610 (estimated)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the present study is to assess the efficacy of methylprednisolone as an adjuvant therapy in patients with severe community-acquired pneumonia (CAP) (PSI 4-5). The hypothesis of the study is that methylprednisolone can decrease the mortality of severe CAP without any significant side effects,with reduction of the time to clinical stability and failure rate of treatment.

Conditions

• Community Acquired Pneumonia

Interventions

Type	Name	Description
DRUG	methylprednisolone
DRUG	Normal saline

Timeline

• Start date: 2015-05-01
• Primary completion: 2017-05-01
• Completion: 2017-05-01
• First posted: 2015-09-17
• Last updated: 2015-09-17

Locations

1 site across 1 country: China