NCT02550964

Incidence and Risk Factor of Hydroxychloroquine and Chloroquine Retinopathy

Incidence and Risk Factor Evaluation for Toxic Maculopathy Associated With Hydroxychloroquine and Chloroquine

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 124 (estimated)
• Sponsor: Asan Medical Center · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the incidence and risk factor of toxic maculopathy who treated with hydroxychloroquine or chloroquine due to their autoimmune disease such as rheumatoid arthritis or systemic lupus erythematosus. Total 5-year of the study periods, the investigators will screen these patients by baseline examination (Fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography, Humphrey visual field test and multifocal electroretinography) and observe with same examination for every year.

Conditions

• Toxic Maculopathy

Interventions

Type	Name	Description
PROCEDURE	Composite Examination	First, patients will get the baseline ophthalmologic exam and medical evaluation by physicians. As a diagnostic method, the composite examination including fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography, Humphrey visual field test and multifocal electroretinography will be tested once every year.

Timeline

• Start date: 2014-01-01
• Primary completion: 2019-01-01
• Completion: 2019-01-01
• First posted: 2015-09-16
• Last updated: 2015-09-18

Locations

1 site across 1 country: South Korea