NCT02549248

Nanoparticles Analysis in Lung and Bronchi During Various Pulmonary Interstitial Diseases and Relationships With Their Aetiology

Nanoparticles Analysis in Lung and Bronchi During Various Pulmonary Interstitial Diseases and Relationships With Their Aetiology. A Monocentric Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Centre Hospitalier Universitaire de Saint Etienne · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Nanoparticles (NP) are particles whose length, width and height are less than 100 nanometres. Over the past decade, industrial applications of NP have increased dramatically. Despite their widespread use, their true impact on human health remains unknown and poorly studied. NP exposure in humans primarily occurs via inhalation through the respiratory system. The aim of this study is to estimate the relationships between the nanoparticle load in the lung and bronchi and some interstitial lung diseases. In the aftermath of human exposure to asbestos, the pathological consequences of environmental exposure to nanomaterials could be evaluated upon a mineralogical analysis of pulmonary samples.

Conditions

• Interstitial Lung Diseases

Interventions

Type	Name	Description
OTHER	BAL	Patients with idiopathic and non idiopathic interstitial lung diseases
OTHER	BW	Patients with idiopathic and non idiopathic interstitial lung diseases
OTHER	EAC	Patients with idiopathic and non idiopathic interstitial lung diseases
OTHER	blood specimen	Patients with idiopathic and non idiopathic interstitial lung diseases
OTHER	Urine specimen	Patients with idiopathic and non idiopathic interstitial lung diseases

Timeline

• Start date: 2012-12-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2015-09-15
• Last updated: 2015-09-15

Locations

1 site across 1 country: France