NCT02547727

Immune Responses After a Four-site Intradermal Rabies Booster Vaccination in HIV-infected Adults

Humoral and Cell-mediated Immune Responses After a Four-site Intradermal Rabies Booster Vaccination in Previously Rabies Immunized HIV-infected Adults

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Queen Saovabha Memorial Institute · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

A four-site intradermal rabies booster vaccination in HIV - infected patients who have ever received primary rabies vaccination could improve their immune response to this kind of vaccine.

Detailed description

A four-site intradermal rabies booster vaccination has shown higher immune response than conventional intramuscular rabies booster vaccination in healthy persons. So, the investigators hypothesized the same outcome in HIV - infected patients.

Conditions

• Rabies

Interventions

Type	Name	Description
BIOLOGICAL	rabies vaccine	Rabies vaccine is injected according to the protocol then blood would be drawn for rabies neutralizing antibody, OX-40 assay and cytokines assessment on day 0,7,14.

Timeline

• Start date: 2016-02-01
• Primary completion: 2023-12-01
• Completion: 2023-12-01
• First posted: 2015-09-11
• Last updated: 2022-04-29

Locations

1 site across 1 country: Thailand