Clinical Trials Directory

Trials / No Longer Available

No Longer AvailableNCT02547675

Rociletinib (CO-1686) USA Expanded Access Program

An Expanded Access Protocol of Oral Rociletinib (CO-1686) as Epidermal Growth Factor Receptor (EGFR)-Directed Therapy for Patients With EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC) With the T790M Resistance Mutation

Status
No Longer Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Clovis Oncology, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers

Summary

To provide access to rociletinib for patients with advanced or metastatic EGFR-mutant NSCLC who have been treated previously with EGFR directed therapy and have evidence of a T790M mutation (T790M+).

Detailed description

This is an open-label, multi-center study in the US, which allows for expanded access to rociletinib for patients with advanced or metastatic, EGFR-mutant T790M+ NSCLC who were previously treated with at least one prior EGFR TKI therapy (≥2nd line). Patients will receive oral rociletinib twice daily on study as long as they have clinical benefit and until they have access to FDA-approved rociletinib.

Conditions

Interventions

TypeNameDescription
DRUGRociletinibRociletinib will be administered to patients orally

Timeline

First posted
2015-09-11
Last updated
2018-09-25

Locations

11 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02547675. Inclusion in this directory is not an endorsement.