NCT02543411

Use of Lidocaine in Endoscopic Submucosal Dissection

Effect of Intravenous Lidocaine During Endoscopic Submucosal Dissection for Gastric Neoplasm

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: Severance Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The primary purpose of this study is to investigate the effects of lidocaine on the total administered dose of fentanyl during sedation for endoscopic mucosal resection. The secondary purpose of this study is to investigate the effects of lidocaine on pain score related with endoscopic mucosal resection at time of 30 min, 6 hr, and 24 hr after procedure.

Conditions

• Gastric Neoplasm

Interventions

Type	Name	Description
DRUG	Lidocaine 1%	Intravenous administration as bolus of lidocaine 1.5 mg/kg before sedation and infusion of lidocaine 2 mg/kg/hr during sedation. Sedation with fentanyl and propofol
DRUG	Normal saline	Intravenous administration as bolus of normal saline 0.15 mL/kg before sedation and infusion of normal saline 0.2 mL/kg/hr during sedation. Sedation with fentanyl and propofol

Timeline

• Start date: 2015-09-01
• Primary completion: 2015-11-01
• First posted: 2015-09-07
• Last updated: 2015-12-15

Locations

1 site across 1 country: South Korea