NCT02542943

Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

A Clinical Study Investigating the Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the longitudinal efficacy of two experimental oral rinses containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX), formulated at pH 4.5 and pH 7 respectively, for the relief of dentinal hypersensitivity (DH), compared to a placebo oral rinse, when used as an adjunct to twice daily brushing with a standard fluoride toothpaste.

Conditions

• Dentin Sensitivity

Interventions

Type	Name	Description
DEVICE	Experimental Oral Rinse 1	(1.5% w/w KOX, pH 4.5)
DEVICE	Experimental Oral Rinse 2	(1.5% w/w KOX, pH 7)
OTHER	Placebo Oral Rinse	(0% w/w KOX, pH 4.5)
DRUG	Standard fluoride toothpaste	1000ppm fluoride as sodium monofluorophosphate

Timeline

• Start date: 2015-09-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2015-09-07
• Last updated: 2017-03-06
• Results posted: 2017-03-06

Locations

1 site across 1 country: United States