NCT02540239

Premedication Simethione Improves Visibility During Bowel Cleansing for Colonoscopy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 590 (actual)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

To evaluate the efficacy, visibility of low volume polyethyleneglycol-simeticone (2-LPEG-S) for colonoscopy.

Detailed description

In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 2 L PEG before colonoscopy. Patients in group B (n = 300) were additionally advised to simeticone plus 2 L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by a single endoscopist who was blinded to the intervention. Visibility was blindly assessed for the amount of air bubbles and adenoma detection rate (ADR). Difficulty of procedure, and adverse events were also evaluated.

Conditions

• Bowel Preparation Scale
• the Amount of Air Bubble
• Adenoma Detection Rate

Interventions

Type	Name	Description
DRUG	2L PEG
DRUG	2L PEG+simethicone

Timeline

• Start date: 2015-01-01
• Primary completion: 2016-02-01
• Completion: 2016-04-01
• First posted: 2015-09-03
• Last updated: 2016-04-19

Locations

1 site across 1 country: China