NCT02539199

Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour

Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour: a Randomized Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 270 (actual)
• Sponsor: Tampere University Hospital · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the effectiveness and safety of vaginally administered misoprostol (Misodel) versus per orally administered misoprostol (Cytotec) in induction of labour in nulliparous women.

Conditions

• Labour Induction

Interventions

Type	Name	Description
DRUG	Misoprostol, modified-release pessary	Misoprostol pessary (7 ug/h) placed in vaginal fornix until labour is induced or maximum 24 hours
DRUG	Misoprostol, per-oral tablets	First day: 50 ug PO in every 4 hours maximum 3 times per day. Second day: 100 ug PO in every 4 hours maximum 3 times per day. Third day: 50 ug vaginally in every 4 hours maximum 3 times per day or until labour is induced.

Timeline

• Start date: 2015-09-01
• Primary completion: 2018-03-02
• Completion: 2018-03-02
• First posted: 2015-09-02
• Last updated: 2018-04-18

Locations

5 sites across 1 country: Finland