NCT02538133

Study Assessing Hybrid SPECT-CT With Labeled Leukocytes for Diagnosis of Vascular Prosthesis Infections

Tomoscintigraphie Hybride Aux Leucocytes Marqués Dans le Diagnostic Des Infections de Prothèses Vasculaires.

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Vascular Prothesis Infection is a rare but an extremely serious complication. Diagnosis is often difficult (germs are found only in 50% of cases). Conventional imagery is often non-specific and difficult to interpret especially in early postoperative phase. Leukocytes isolated from the patient's blood are labeled with a radiopharmaceutical technetium 99mTc-HMPAO. The aim of this study is to assess the overall diagnostic performance of scintigraphy (hybrid SPEC-CT) with labeled leucocytes in diagnosis of subdiaphragmatic vascular prothesis infection.

Conditions

• Vascular Prosthesis Infection

Interventions

Type	Name	Description
BIOLOGICAL	99mTc-Exametazime (HMPAO)-labeled leukocytes	Hybrid tomoscintigraphy with labeled leucocytes for patients with suspected vascular prosthesis infection

Timeline

• Start date: 2015-09-01
• Primary completion: 2020-01-01
• Completion: 2020-01-01
• First posted: 2015-09-02
• Last updated: 2019-03-07

Locations

3 sites across 1 country: France