NCT02535819

Endothelial Cell Loss After Phacoemulsification Intra and Supracapsular

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 294 (actual)
• Sponsor: Centre Hospitalier Régional Metz-Thionville · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cataract is the clouding of the lens of the eye, which initially prevents clear vision and eventually progresses to blindness if left untreated. Cataract remains the leading cause of blindness and an important cause of visual impairment across the globe. Cataract surgery by ultrasonic phacoemulsification is the most common surgery practiced in France (600 000/year) Two sub-categories of phacoemulsification coexist : Endocapsulars techniques represented by Divide-and-Conquer and Phaco-Chop ; and Supracapsular techniques mainly represented by Subluxation (similar to Tilt-and-Tumble) The corneal endothelium plays an important role in maintaining the dehydrated state and the transparency of the cornea. Some degree of endothelial cell loss invariably occurs in all types of cataract surgery but the amount of endothelial cell loss may varies with the type of surgical technique The aim of the study is to evaluate the density of the central corneal endothelial cells before and after cataract surgery comparing two phacoemulsification techniques (Divide-and-Conquer vs Subluxation)

Conditions

• Cataracts

Interventions

Type	Name	Description
PROCEDURE	Subluxation	One pole of The nucleus is hydrodissected until it lilts above the capsular bag. The tilted nucleus is rotated to face the incision and remaining half nucleus is then tumbled and emulsification continues from the opposite equator outside in until complete
PROCEDURE	Divide and Conquer	Cataract nucleus is fragmented into 4 pieces then aspirated by ultrasonic vibration

Timeline

• Start date: 2015-06-01
• Primary completion: 2017-09-01
• Completion: 2018-05-01
• First posted: 2015-08-31
• Last updated: 2019-04-16

Locations

1 site across 1 country: France