Clinical Trials Directory

Trials / Completed

CompletedNCT02531867

Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan

A Multicenter, Post-Approval Clinical Study for Asfotase Alfa (Human Recombinant Tissue-nonspecific Alkaline Phosphatase Fusion Protein) Treatment for Patients With Hypophosphatasia (HPP) in Japan

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
13 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This is a multicenter study in Japan. Eleven sites which have already participated in the investigator-initiated clinical study (Early Access Program) will participate in this study.The objective of this study is to gain further information on the safety and efficacy of treatment with asfotase alfa.

Detailed description

The primary objective of this study was to collect data on the safety of repeated subcutaneous (SC) injections of asfotase alfa. There were no secondary objectives. Exploratory objectives related to the efficacy of asfotase alfa are not being reported.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAsfotase Alfa

Timeline

Start date
2015-06-01
Primary completion
2015-11-01
Completion
2015-11-01
First posted
2015-08-25
Last updated
2017-05-08
Results posted
2017-05-08

Source: ClinicalTrials.gov record NCT02531867. Inclusion in this directory is not an endorsement.

Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan (NCT02531867) · Clinical Trials Directory