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Trials / Completed

CompletedNCT02531113

Efficacy and Safety Trial of RPC1063 for Moderate to Severe Crohn's Disease

A Phase 2, Multi-Center, Open-Label Induction Trial With Extension Period to Access Endoscopic Improvement and Changes in Intestinal and Serum Biomarkers in Patients With Moderately to Severely Active Crohn's Disease Receiving Oral RPC1063 as Induction Therapy

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
69 (actual)
Sponsor
Celgene · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose is to determine whether RPC1063 is effective in the treatment of Crohn's disease.

Detailed description

This open-label trial is composed of two periods: Induction and Extension. All eligible patients will be enrolled into the 12-Week Induction period and receive study medication. Patients who complete the Induction period may then be eligible to enter the 100-Week Extension period where they will continue to receive study medication.

Conditions

Interventions

TypeNameDescription
DRUGRPC1063

Timeline

Start date
2015-10-09
Primary completion
2019-09-12
Completion
2019-11-28
First posted
2015-08-24
Last updated
2021-01-22
Results posted
2020-10-08

Locations

28 sites across 5 countries: United States, Canada, Hungary, Poland, Ukraine

Source: ClinicalTrials.gov record NCT02531113. Inclusion in this directory is not an endorsement.

Efficacy and Safety Trial of RPC1063 for Moderate to Severe Crohn's Disease (NCT02531113) · Clinical Trials Directory