NCT02525107

Prevention of Vaso-occlusive Painful Crisis by Using Omega-3 Fatty Acid Supplements

Omega 3 Fatty Acid Therapy for Prevention of Vaso-occlusive Crisis and Manifestations in Omani Patients With Sickle Cell Disease

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 280 (estimated)
• Sponsor: Sultan Qaboos University · Academic / Other
• Sex: All
• Age: 13 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

140 SCD patients \[70 on Hydroxyurea\] will receive Omega-3 capsules whereas another 140 SCD patients \[70 on Hydroxyurea\] will receive placebo and will be recruited from the Sultan Qaboos University Hospital \[SQUH\] haematology specialty clinics. Patients will be randomized in a 1:1 ratio to receive placebo or Omega-3 for 52 weeks. The aim is to investigate the therapeutic potential of omega-3 fatty acids in the prevention of vaso-occlusive crisis in Omani patients with sickle cell disease\[SCD\].

Conditions

• Sickle Cell Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Omega-3 capsules	SCD patients on Hydroxyurea
DIETARY_SUPPLEMENT	Placebo	SCD patients on Hydroxyurea
DIETARY_SUPPLEMENT	Omega-3 capsules	SCD patients not on Hydroxyurea
DIETARY_SUPPLEMENT	Placebo	SCD patients not on Hydroxyurea

Timeline

• Start date: 2015-09-01
• Primary completion: 2019-01-01
• Completion: 2019-03-01
• First posted: 2015-08-17
• Last updated: 2015-08-17

Locations

1 site across 1 country: Oman