Clinical Trials Directory

Trials / Terminated

TerminatedNCT02524288

Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)

A Phase 3, Single Arm, Clinical Trial to Study the Contraceptive Efficacy and Safety of the MK-8342B (Etonogestrel + 17β-Estradiol) Vaginal Ring in Healthy Women 18 Years of Age and Older, At Risk for Pregnancy

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
1,941 (actual)
Sponsor
Organon and Co · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess the contraceptive efficacy of the Etonogestrel (ENG) + 17β-Estradiol (E2) vaginal ring in women between 18 and 35 years of age based on the number of in-treatment pregnancies as expressed by the Pearl Index (PI). The study will also assess the safety and tolerability of the ENG-E2 vaginal ring.

Conditions

Interventions

TypeNameDescription
DRUGENG-E2 125 μg/300 μg vaginal ringUp to 13 cycles of ENG-E2 125 μg/300 μg administered intravaginally, each cycle consisting of 21 days of vaginal ring use followed by 7 vaginal ring-free days.

Timeline

Start date
2015-08-31
Primary completion
2016-09-16
Completion
2016-09-16
First posted
2015-08-14
Last updated
2024-05-17
Results posted
2017-09-25

Regulatory

Source: ClinicalTrials.gov record NCT02524288. Inclusion in this directory is not an endorsement.