Trials / Completed
CompletedNCT02522026
Follow-up-study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers
Follow-up-study of Participants (COPD Patients and Healthy Control Subjects) From the Cross-sectional Study "11-03 Ribolution" for the Evaluation of Predictive Biomarkers Based on Non-coding RNA
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 116 (actual)
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
Between 2012 and 2014, a cohort of 90 COPD subjects of disease severity grades GOLD I-IV as well as 60 healthy control subjects (30 smokers and 30 non-smokers) have been examined regarding different clinical and blood/ sputum derived biomarkers at the investigators' research center. This observation study will follow-up/re-examine all available subjects regarding disease course and treatment changes after 3 years (+/-6 months) for the investigation of ncRNA/ transcriptome biomarkers for their potential to indicate disease progression. In addition, biobanking of respective biosamples for potential future COPD biomarker research will be conducted.
Conditions
Timeline
- Start date
- 2015-08-01
- Primary completion
- 2017-03-01
- Completion
- 2017-03-01
- First posted
- 2015-08-13
- Last updated
- 2025-02-25
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT02522026. Inclusion in this directory is not an endorsement.