Trials / Completed
CompletedNCT02513147
HIV Reservoir Dynamics After Switching to Dolutegravir in Patients on a PI and 2 NRTI Based Regimen
HIV Reservoir Dynamics After Switching to Dolutegravir in Patients With Two NRTI and a Protease Inhibitor Based Regimen. A Phase IV Open Randomized Trial
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 44 (actual)
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to assess changes in viral reservoir after changing IP/r to dolutegravir in HIV-1 infected patients maintaining undetectable viral load on Antiretroviral Therapy (ART).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dolutegravir | |
| DRUG | PI | (Fosamprenavir, atazanavir, lopinavir or darunavir) boosted with 100 mg of ritonavir, or atazanavir (400 mg / d) not boosted with ritonavir,if the 2 NRTIs are abacavir + Lamivudine |
| DRUG | 2 NRTI | |
| DRUG | 2 NRTI |
Timeline
- Start date
- 2015-06-01
- Primary completion
- 2016-11-01
- Completion
- 2016-11-01
- First posted
- 2015-07-31
- Last updated
- 2017-06-14
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT02513147. Inclusion in this directory is not an endorsement.