NCT02512224

Comparison of Outcomes Between Parenteral and Enteral Nutrition

Comparison of Short-term Mortality and Morbidity Between Parenteral and Enteral Nutrition for Adults Without Cancer: a Propensity-matched Analysis Using a National Inpatient Database

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 5,824 (actual)
• Sponsor: Tokyo University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Short-term outcomes of parenteral and enteral nutrition for patients unable to eat normally were compared and analyzed.

Detailed description

Data were acquired from patients selected from a national inpatient database covering 1,057 hospitals in Japan. Participants had received artificial nutrition between April 2012 and March 2013, were 20 years or older, and did not have cancer. Participants were grouped into two groups: those receiving parenteral nutrition and those receiving enteral nutrition. The investigators performed one-to-one propensity-score matching between the groups. The primary outcome measurements were mortality rates at 30 and 90 days after the start of the procedure. The secondary outcomes were post-procedural complications, pneumonia, and sepsis. The investigators analyzed survival length of stay after the procedure using a Cox proportional hazards model.

Conditions

• Deglutition Disorders

Interventions

Type	Name	Description
DEVICE	Parenteral nutrition	Participants are retrospectively selected with propensity score matching
DEVICE	Enteral nutrition	Participants are retrospectively selected with propensity score matching

Timeline

• Start date: 2012-04-01
• Primary completion: 2013-03-01
• Completion: 2014-12-01
• First posted: 2015-07-30
• Last updated: 2015-09-30
• Results posted: 2015-09-10