NCT02512146

The Expression of the Ionotropic Glutamate Receptors in Colon of IBS

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Shandong University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The study aims to determine the expression of the ionotropic glutamate receptors in colon of irritable bowel syndrome (IBS) patients and evaluate the relationship between the ionotropic glutamate receptors and IBS symptoms.

Detailed description

Ionotropic glutamate receptors participate in pain in nervous system. In this study,participants will examine the expression of the ionotropic glutamate receptors in colon of irritable bowel syndrome (IBS) patients and evaluate the relationship between the ionotropic glutamate receptors and IBS symptoms. Participants may futher study the mechanism using cell experiment.

Conditions

• Irritable Bowel Syndrome

Interventions

Type	Name	Description
PROCEDURE	colonoscopy	Patients will undergo colonoscopy and participants will get biopsies from the colon.

Timeline

• Start date: 2015-06-01
• Primary completion: 2016-04-01
• Completion: 2016-06-01
• First posted: 2015-07-30
• Last updated: 2015-07-30

Locations

1 site across 1 country: China